한캄무역 상황버섯 :: 캄보디아 상황버섯 에관한 미국생물정보센타(NCBI) 홈페이지 내역

캄보디아 상황버섯은 살아있는 산뽕나무에서 산뽕나무의 우유빛수액을 빨아먹으며 자란 상황버섯이

진짜 상황버섯으로써 린테우스 상황버섯 바우미 상황버섯으로 불리우며

상황버섯 효능으로는 이시대에 하나님께서 내려주신 마지막선물이라 할정도로 뛰어난 효능이 입증된 것으로

말굽형태로 생긴 말굽 상황버섯과 부채꼴 형태로 생긴 부채꼴 상황버섯 두가지로 구분 된다.

상황버섯 효능,상황버섯효과메시마코부 상황버섯, 상황버섯 먹는방법,상황버섯 달이는방법

은 한캄무역 상황버섯 홈페이지를 참작해주시면 도움이 되실것입니다.

미국 생물정보센터(NCBI) 홈페이지에 한국의 경희대학교 동서의학대학원와 서울대학교 수의과대학 대학원 공동으로 발표한

캄보디아 상황버섯의 항암 및 면역조절 작용에 대한 연구
논문이 개재 되었읍니다.

.** 캄보디아 상황버섯을 유전자 분석결과 99%의 homology를 가지는Phellinus Linteus 라는 부분이 눈에 띄는군요.
특별한 암전이 억제능력으로 폐암전이 억제효과가 있음을 밝히고 있읍니다..

(미국생물정보센타(ncbi) 홈페이지주소)
www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=search&term=cambodia+linteus

Cambodian Phellinus linteus inhibits experimental metastasis of melanoma cells in mice via regulation of urokinase type plasminogen activator.

Lee HJ, Lee HJ, Lim ES, Ahn KS, Shim BS, Kim HM, Gong SJ, Kim DK, Kim SH.

Department of Oncology, Graduate School of East-West Medical Science, Kyunghee University, Yongin, Kyunggi-do, Republic of Korea.

Phellinus linteus (PL) is a fungus mainly found in tropical America, Africa and Asian countries including Korea, Japan and China. PL has been traditionally used for the treatment of arthritis, liver damage and cancer.

However, little was known on the biological activity and characterization of Phellinus species in Cambodia.

Thus, in the present study, the anti-metastatic mechanism of aqueous extract of Cambodian Phellinus linteus (CPL) was evaluated.

Cambodian mushroom was identified as a Phellinus species with 99% homology of Phellinus linteus by DNA sequence analysis and comparison by the National Center for Biotechnology Information

CPL did not exhibit any significant cytotoxicity against B16BL6 cells, invasive melanoma cells at 1 mg/ml. However, CPL inhibited platelet aggregation induced by B16BL6 cells and also disrupted the adhesion to gelatin and invasion of B16BL6 cells in a concentration dependent manner.

Similarly, CPL dose-dependently inhibited the pulmonary metastatic colonies in C57BL/6 mice intravenously injected by B16BL6 cells up to 55.5% at a dose of 50 mg/kg compared with untreated control.

CPL also down-regulated the expression of urokinase type plasminogen activator (uPA), one of key proteins associated with invasion and metastasis of tumor cells in a concentration dependent fashion, while CPL didn't significantly affect the expression of matrix metalloproteinase 2 (MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) by reverse transcriptase-polymerase chain reaction (RT-PCR).

Taken together, these findings indicate that Cambodian Phellinus linteus may inhibit metastasis at least partly via regulation of uPA associated with tumor cell induced platelet aggregation (TCIPA) and also suggest a further study for isolation of active ingredients and the involvement of adhesion molecule signaling pathway.

PMID: 15635158 [PubMed - indexed for MEDLINE]